Rogers A, Obst S, Teague SJ, et al. - Via performing a systematic review and meta-analysis, researchers here examined if and how maternal perinatal depression and anxiety are linked with social-emotional, cognitive, language, motor, and adaptive behavior development in offspring during the first 18 years of life. They searched six databases (CINAHL Complete, Cochrane Library, Embase, Informit, MEDLINE Complete, and PsycInfo) identifying 27,212 articles; of these, 191 were eligible for meta-analysis. Evidence suggests maternal perinatal depression and anxiety to be correlated with poorer social-emotional, cognitive, language, motor, and adaptive behavior development in offspring. Extension of developmental outcomes beyond infancy, into childhood and adolescence was suggested. Maternal perinatal depression and anxiety thus represent important targets for prevention and early intervention to support mothers transitioning into parenthood and the health and well-being of next-generation offspring.