Zhao S, Yu S, Chi C, et al. - In an elderly community-dwelling Chinese population from the Northern Shanghai Study, researchers explored how the emerging triglyceride-glucose (TyG) index is connected to macrovascular (arterial stiffness, lower extremity atherosclerosis, carotid hypertrophy, and carotid plaque) and microvascular damage (chronic kidney disease and microalbuminuria). A total of 2,830 elderly participants were enrolled. According to findings, an elevated TyG index was significantly linked to a higher risk of arterial stiffness (carotid-femoral pulse wave velocity (PWV) > 10 m/s or brachial-ankle-PWV > 1,800 cm/s) and nephric microvascular damage. However, the TyG index showed no significant connection to lower extremity atherosclerosis, carotid hypertrophy or carotid plaque. This finding provides support for the clinical significance of the TyG index for evaluating vascular damage.