Vavanikunnel J, et al. - In this study involving 3,329 type 1 (T1DM) and 44,275 type 2 diabetes mellitus (T2DM) patients, researchers assessed the relationship between the level of glycemic control and the risk of low-trauma fractures. Eligible study participants were newly diagnosed with T1DM or T2DM between 1995 and 2015. For both T1DM and T2DM, median duration between diabetes onset and fracture date was 4.5 years. Compared with T1DM patients with mean HbA1c values ≤ 7.0%, the risk of fracture was increased in T1DM patients with mean HbA1c values > 8.0%. Regardless of glycemic control, the risk of fracture in patients with T2DM and current use of rosiglitazone and pioglitazone was increased. According to findings, the impact of glycemic control on the risk of low-trauma fracture varies between patients with T1DM and T2DM. Poor glycemic control increased the risk of fracture in patients with T1DM but not in patients with T2DM.