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Association between gaps in antihypertensive medication adherence and injurious falls in older community-dwelling adults: A prospective cohort study

BMJ Open Mar 08, 2019

Dillon P, et al. - In community-dwelling, long-term (≥ 1 year) antihypertensive medication users aged ≥ 65 years, researchers assessed the correlation between gaps in antihypertensive medication adherence and injurious falls. Gaps in antihypertensive drug adherence were assessed as the number of 5-day gaps between sequential supplies over the 12-month period prior to baseline from linked dispensing records. In this prospective cohort study involving 938 participants, each 5-day gap in antihypertensive refill adherence increased the risk of self-reported injurious falls by 18%. Findings suggested that gaps in antihypertensive adherence could be a marker for increased risk of injurious falls. It remains unknown, however, whether subsequent risk may be reduced by adherence interventions, thus warranting further study.

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