Roberts BW, et al. - In this preplanned analysis of a prospective cohort study involving adult, nontraumatic cardiac arrest patients treated with targeted temperature management after return of spontaneous circulation in 6 academic hospitals in the United States, researchers investigated whether elevated postresuscitation mean arterial blood pressure was associated with neurologic outcome. Using noninvasive measures, mean arterial blood pressure was recorded after return of spontaneous circulation and every hour during the initial 6 hours thereafter. A modified Rankin Scale less than or equal to 3 defined good neurologic function. At hospital discharge, prospective determination of the modified Rankin Scale was also done. A mean arterial blood pressure greater than 90 mm Hg was reported in 159 (59%) of 269 patients included. Findings revealed an independent association of elevated blood pressure during the initial 6 hours after resuscitation from cardiac arrest, with good neurologic function at hospital discharge.