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Association between chronic pain and long-term cognitive decline in a population-based cohort of elderly participants

Pain Jan 27, 2021

Rouch I, Edjolo A, Laurent B, et al. - Researchers performed this prospective study to determine the link between chronic pain (CP) and the change in several tests evaluating memory, attention, verbal fluency, and processing speed. The participants were enrolled from the PAQUID study, a cohort of community dwellers aged 65 years and older; there were 693 persons undergoing a pain assessment included. They found a significant correlation between CP and poorer 15-year scores on global cognitive performance, and particularly, a higher slope of decline was noted in relation to the Digit Symbol Substitution Test. Overall, findings revealed higher cognitive decline, particularly in processing speed, in relation to chronic pain. This observation supports that actively treating CP with pharmacological and nonpharmacological strategies is an important step to avert consequences, like cognitive outcomes.

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