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Association between body mass index and surgical menopausal symptoms in patients with early stage endometrial cancer

Gynecologic Oncology Mar 24, 2019

Cripe JC, et al. - A total of 166 endometrial cancer patients who underwent menopause secondary to surgical staging were retrospectively examined to assess the link between body mass index (BMI) and surgical menopausal symptoms. Severe symptoms were defined as those for which treatment was prescribed; mild symptoms were defined as those for which treatment was offered but declined. As appropriate, ANOVA and Chi-square tests were used to perform univariate analysis. Using Poisson regression models, researchers generated relative risks (RR). Overall 33 (19.9%) had BMI <30, 49 (29.5%) had BMI 30–39.9, 50 (30.1%) had BMI 40–49.9, and 34 (20.5%) had BMI ≥50. The groups did not differ in terms of race, age, or adjuvant treatment. Compared with women with BMI <30, a significantly lower likelihood of experiencing menopausal symptoms after oophorectomy was reported in women younger than 50 with BMI >40 and stage I endometrial cancer.

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