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Association between admission lactate levels and mortality in patients with acute coronary syndrome: A retrospective cohort study

Coronary Artery Disease Dec 13, 2018

Liang D, et al. - In a total of 1,865 consecutive patients with acute coronary syndrome (ACS) who were admitted to the Coronary Care Unit of the First Affiliated Hospital of Wenzhou Medical University between 2014 and 2017, researchers evaluated the impact of admission lactate level on ACS prognosis in this retrospective observational study. Patients were categorized into tertiles of lactate level (T1: <1.8; T2: 1.8–2.6; T3: ≥2.7 mmol/l). Admission lactate level was found to be significantly and positively associated with both 180-day and 30-day mortality, with highest risk for lactate greater than or equal to 2.7 mmol/l. Overall, elevated admission lactate level was identified as an independent predictor of 30-day and 180-day all-cause mortality in this patient population.
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