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Assessment of adherence to asthma controllers in children and adolescents

Pediatric Allergy and Immunology Jul 26, 2020

Marckmann M, Hermansen MN, Hansen KS, et al. - Considering that low adherence to asthma controllers is known to raise the likelihood of uncontrolled disease and poor health outcomes, researchers examined risk factors of long‐term adherence to preventive medications in children and adolescents with asthma. In 155 children with asthma followed in a tertiary pediatric asthma outpatient clinic using percentage of days covered based on physician prescriptions and pharmacy claims data, adherence was measured over a two-year period. In the study period, 95 children, 50 (53%) males, mean age 16.3 years (SD, 2.36), received at least one prescription for asthma controllers. Findings indicate that low adherence to preventive medication among half of the children with asthma, correlated with rising age and fractional exhaled nitric oxide (FeNO) level. Additional efforts should, therefore, be directed toward teenagers who are switching from pediatric to adult medicine and toward inhaled corticosteroid‐treated patients with elevated FeNO to increase their adherence to asthma controllers.

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