de Asteasu MLS, Martínez-Velilla N, Zambom-Ferraresi F, et al. – In this secondary analysis of a randomized clinical trial carried out from February 1, 2015, to August 30, 2017, in an Acute Care of the Elderly unit in a tertiary public hospital (Spain) with 370 hospitalized individuals (aged ≥ 75 years) who were randomized to an exercise intervention (n = 185) or a control (n = 185) group, researchers evaluated the impact of a multicomponent exercise intervention for cognitive function in elderly adults during acute hospitalization. The physical exercise program offered important advantages over usual care. A mean increase of 0.1 m/s and 0.1 m/s in the verbal Gait Velocity Test (GVT) and in the arithmetic GVT, respectively, over the usual care group, was exhibited by the exercise group at discharge. An obvious improvement in the intervention group also in the Trail Making Test Part A score and the Mini-Mental State Examination score was observed. Notable advantages for the verbal fluency test over the usual care group were also identified in the exercise group. Hence, in very old patients during acute hospitalization, an individualized, multicomponent exercise training program may be an efficient therapy for enhancing cognitive function (ie, executive function and verbal fluency domains). The demand for a shift from the traditional (bedrest-based) hospitalization to one that identifies the significant role of maintaining functional capacity and cognitive function in elderly adults, chief components of intrinsic capacity, was supported in this secondary analysis.