Khan TS, et al. - In this retrospective cohort study, the researchers examined the risk of obtaining a nondiagnostic sample with ultrasound-guided thyroid fine-needle aspiration and biopsy (FNAB) in patients taking antithrombotic or anticoagulant (AT/AC) medications. This study was conducted on five hundred fifty-six patients who underwent thyroid FNAB. Using the Bethesda classification, all cytology samples were reported. In patients taking aspirin, this was the first study to demonstrate a 3-fold independently greater risk of a nondiagnostic FNAB cytology. This study highlighted the importance of assessing the need for continuation of aspirin in patients undergoing thyroid FNAB as this could affect the diagnostic yield of the procedure.