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Aspirin and preeclampsia prevention in women with preexisting diabetes: A retrospective study

Internal Medicine Journal Mar 08, 2021

Lah S, Cheung NW, Lee V, et al. - For prevention of preeclampsia in high risk pregnancies, aspirin is routinely prescribed. Researchers sought to determine its efficacy and safety in women with pre‐existing diabetes who attended antenatal clinics. They included a total of 164 women with pre‐existing diabetes who attended antenatal clinics in a tertiary referral hospital; 45 of these received aspirin. The baseline risk of preeclampsia and placental insufficiency was higher for the women in the aspirin group. There were no differences between the aspirin and control groups with respect to preeclampsia or any other measure of placental insufficiency; this favors the efficacy of aspirin. A potential complication of aspirin therapy was PPH, and early pregnancy HbA1c was identified as a novel risk stratification tool for preeclampsia in women with preexisting diabetes.

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