Klyne DM, et al. - In view of the considered pathophysiological role of central sensitization in chronic low back pain (LBP), researchers examined if individuals who did and did not recover by 6 months differ regarding sensory profiles during acute LBP. In addition, they sought subgroups associated with outcomes. Individuals with acute LBP (<2 weeks of onset; N = 99) completed questionnaires related to pain/disability, sleep, and psychological status and then underwent pain threshold (heat/cold/pressure) and conditioned pain modulation testing. They performed a comparison of sensory measures during the acute phase (baseline) and longitudinally (baseline/6 months) between unrecovered (greater or unchanged pain and disability), partially recovered (improved but not recovered pain and/or disability), and recovered (no pain and disability) participants at 6 months. The groups did not differ regarding sensory measure at either time point. Findings suggest resolution of central sensitization during the acute phase for many patients. However, when combined with other psychological features, it may be a precursor to the transition to chronicity.