Wallis O, et al. - Via conducting bivariate and multivariable regression analyses, researchers studied the demographic, disease-related, and psychological factors associated with anxiety in patients with multiple sclerosis (MS). They analyzed cross-sectional data from 119 patients with MS. According to findings, 42% of patients with MS had clinically significant levels of anxiety, which was defined by a score ≥ 8 on the anxiety subscale of the Hospital Anxiety and Depression Scale. Furthermore, a significant association between anxiety and depressive symptoms, fatigue, cognitive complaints, and psychiatric history were observed. Only depressive symptoms and cognitive complaints remained significantly associated with anxiety in the multivariable analysis. The authors concluded that anxiety is common in patients with MS, and it is most strongly associated with psychological factors.