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Anxiety at age 15 predicts psychiatric diagnoses and suicidal ideation in late adolescence and young adulthood: Results from two longitudinal studies

BMC Psychiatry Nov 22, 2019

Doering S, Lichtenstein P, Gillberg C, et al. - Researchers investigated how various levels of adolescent anxiety relate to psychiatric diagnoses (anxiety-, bipolar/psychotic-, depressive-, and alcohol and drug misuse disorders) and suicidal ideation in early adulthood after adjusting for childhood attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and developmental coordination disorder (DCD). In addition, they determined the proportion attributable to the various anxiety levels for the outcomes. Analyzing a nation-wide population-based Swedish twin study comprising 14,106 15-year-old twins born in Sweden between 1994 and 2002, they identified predictive value of adolescent anxiety, of various levels, for anxiety disorders: hazard ratio (HR) = 4.92 (CI 3.33–7.28); depressive disorders: HR = 4.79 (3.23–7.08), and any psychiatric outcome: HR = 3.40 (2.58–4.48), while adjusting for ADHD, ASD, and DCD. The results were replicated in the Dutch data from a sample consisting of 9,211 Dutch twins, born between 1985 and 1999.
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