Mazzarello V, et al. – The authors performed this study to evaluate the antiwrinkles action of adhesive pads during the time, and the temporary improvement of facial skin appearance by reducing the vision of linear wrinkles and improving skin elasticity. In the crow's feet area, the use of topical adhesive pads improved wrinkles in the first hour after use. However, patient self–evaluation demonstrated that in crow's feet zone, the use of topical adhesive pads for 3 weeks could offer a subjective improvement over a 2 hour period. Topical adhesive pads were safe to use and tolerable for most users.