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Antidiabetic medication use in commercially‐insured children and adolescents in the United States from 2004 to 2019

Diabetes, Obesity and Metabolism Nov 03, 2020

Sun JW, Hernández‐Díaz S, Bourgeois FT, et al. - Researchers conducted the study for describing the patterns of non‐insulin antidiabetic medication use, initiation, and adherence in the pediatric population. They performed a descriptive study of non‐insulin antidiabetic medication use in children and adolescents (10‐18 years) utilizing real‐world data from a nationwide US commercial claims database (January 2004‐September 2019). Trends in the prevalence of non‐insulin antidiabetic medication use overall and by class have been assessed. The prevalence of any non‐insulin antidiabetic medication use was 75.7 per 100,000 patients in 2004 and more than doubled to 162.0 per 100,000 in 2019 in a cohort of > 1 million pediatric patients. Between 2004 and 2019, there was a substantial increase in non‐insulin antidiabetic medication use among commercially‐insured pediatric patients. Almost all patients received metformin medication, although the use of newer agents remained low. Despite the rise in medication use, short treatment episodes have been observed, even among patients diagnosed with type 2 diabetes, raising concern for poor adherence.

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