Antibodies against carbamylated vimentin exist in systemic lupus erythematosus and correlate with disease activity
Lupus Mar 11, 2020
Li Y, et al. - Researchers tried to find out the levels of serum anti-CarP antibodies and to assess their clinical value in systemic lupus erythematosus (SLE). They assessed serum levels of antibodies against carbamylated-vimentin (anti-Carp) by enzyme immunosorbent assay in 100 patients with SLE, 76 with RA, 17 with primary Sjögren syndrome (pSS), and 68 healthy controls. This study carried out data analyses between anti-Carp antibodies and performed other laboratory measures using SPSS 24 software for Windows. In SLE patients, anti-CarP antibodies were present and correlated with the disease severity. These might give a potential supplement to other specific autoantibodies for the diagnosis of SLE and work as a promising marker for estimating joint damage in the disease.
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