Chen YL, et al. – Researchers performed a multistage, clustered, and random sampling with a field-interviewer-administrated survey to examine multiple uses of antibiotics in patients with allergic rhinitis, conjunctivitis, chronic urticaria, and asthma in the grasslands of northern China. The study sample consisted of 5,787 subjects with allergy-related diseases. The prevalence of all four diseases was considerably high in the grasslands due to seasonal pollen exposure. However, no causality could be proven; overuse of antibiotics could be associated with an increased risk of allergy-related disease in later life. But, in contrast to patients who had no multiple antibiotic use, there was an elevation in the prevalence of multiple antibiotic users across the different age groups with the increasing number of common allergy-related diseases. Therefore, to ignore the unnecessary use of antibiotics, improvements in the implementation of the evidence-based international guidelines for the management of allergy-related diseases are needed.