Antibiotic choice and duration associate with repeat prescriptions in infective asthma exacerbations
The Journal of Allergy and Clinical Immunology: In Practice Sep 01, 2018
Stolbrink M, et al. - Using the Optimum Care Database, researchers analyzed prescriptions of antibiotics for lower respiratory tract infections (LRTI) in UK primary care from 2010 to 2015 to describe the demographics of and antibiotic prescriptions for adult asthma patients with LRTI as well as examined factors correlated with repeat antibiotic courses. In univariable analysis, co-morbidities, vaccinations, asthma treatment and exacerbation number were only significant. Multivariable analysis showed that age, index antibiotic and duration, smoking status, location, number of consultations and oral steroid courses in the previous year were significantly correlated with repeat prescription. According to the findings obtained, the current index prescribing preference of 7 days of amoxicillin correlated to fewer repeat courses. Findings suggested no association of baseline asthma treatment with the risk of further prescriptions.
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