Herrman H, et al. - In this prospective, randomized, double-blinded study, researchers studied the safety and impact on seizure frequency of anterior thalamic nucleus deep brain stimulation (DBS). For 12 months, patients were followed. In terms of active stimulation, the first 6 months were blinded or not. All patients received active stimulation after 6 months. Bilateral ANT electrodes have been implanted in 18 patients with focal and pharmacoresistant epilepsy. The Liverpool seizure severity scale (LSSS) was used to measure the epilepsy burden. The study supports the results of previous studies on DBS as a safe treatment option, with effects even in patients with severe, refractory epilepsy. The outcomes were not as encouraging, however, as reported by many other, mainly unblinded and open studies.