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Antenatal iron supplementation and birth weight in conditions of high exposure to infectious diseases

BMC Medicine Aug 01, 2019

Verhoef H, Mwangi MN, Cerami C, et al. - The researchers re-analyzed data from a previous trial in Kenya and exhibited that, because women who were initially iron-deficient respond better to iron supplementation, they exhibit an elevation in birthweight. There was proof that this advantage was reduced in iron-replete women, possibly due to the adverse impacts of haemoconcentration that could impair oxygen and nutrient transfer across the placenta. The Papua New Guinean results might be described by a similar differential response to the iron supplements that they all got. In iron-supplemented people, antenatal iron supplementation should ideally be consumed in conjunction with measures to limit, discover and treat malaria given the capacity of pathogenic microorganisms to proliferate. Nevertheless, even where services to prevent and treat malaria were poor, current evidence suggested the conclusion that the advantages of universal iron supplementation overweighed its risks.

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