McCall SJ, et al. - Researchers focused on anaphylaxis-related hospitalizations during pregnancy in the United States, examining the incidence, temporal trends, as well as potential risk factors. They used the 2004–2014 National Inpatient Sample, United States, to identify all hospitalizations while pregnant and any anaphylactic reactions in accordance with International Classification of Diseases, Ninth Revision, Clinical Modification codes. An increasing trend in anaphylaxis was not evident, despite heightened rates of cesarean delivery in the United States and consequent drug administration. Cesarean delivery vs noncesarean delivery; history of an allergic reaction vs no history; and a black race and other race vs white race were documented as 3 factors that raised the odds of anaphylaxis during pregnancy, after adjustment. The detection of women at risk of anaphylaxis was enabled by cesarean delivery and history of an allergic reaction. Clear risk factors were not present in all women. To be well-prepared to timely manage the occurrence of this uncommon event was recommended.