Yennu SJ, et al. - Researchers evaluated 1,501 consecutive cancer patients referred to a supportive care clinic from March 1, 2016 to June 6, 2018, to investigate the links between current tobacco smoking, daily opioid use, pain response, and risk for aberrant opioid use behaviors (AOB). Eligibility criteria included cancer diagnosis and being on opioids for pain for at ≥ 1 week. The Edmonton Symptom Assessment Scale (ESAS), SOAPP-14 (validated questionnaire for assessment of risk for aberrant opioid use behaviors), and CAGE-AID were used to assess study participants. Findings revealed an increased risk of AOB among male patients and those with history of current or previous smoking history, anxiety, and prior alcoholism/illicit drug use.