Vajaranant TS, et al. - Among 1636 postmenopausal women (mean age ± SD, 69.57±3.64 years; 90.39% white) without glaucoma or ocular hypertension, researchers ascertained whether a larger cup-disc ratio [defined as greater than 0.6 in either eye based on stereoscopic optic nerve photographs] was correlated with poor cognitive function. Data from the Women’s Health Initiative (WHI), originally designed to test effects of hormone therapy (HT) on various health outcomes, were used. According to findings, lower global cognitive function was shown by postmenopausal females who had a large cup-to-disk ratio without glaucoma or ocular hypertension.