Howell JB, et al. - Researchers retrospectively reviewed children with confirmed hearing loss identified through universal newborn hearing screening (UNHS) in Virginia from 2010 to 2014, to compare children with unilateral hearing loss (UHL) to bilateral hearing loss (BHL) regarding the incidence of Joint Committee on Infant Hearing (JCIH) risk factors. A confirmed hearing loss developed in 1004 children (0.20% of all births) over the 5-year study period. Among these, at least one JCIH risk factor was recorded in 544 (51%) children; of these, 226 (42%) had UHL and 318 (58%) had BHL. Neonatal indicators (69%), craniofacial anomalies (30%), stigmata of HL syndromes (14%), and family history (14%) were the most common risk factors for UHL. Neonatal indicators (49%), family history (27%), stigmata of HL syndromes (19%), and craniofacial anomalies (16%) were the most common risk factors in BHL. Higher tendency for BHL was reported for children with the risk factor for positive family history, while UHL risk was higher for those with craniofacial anomalies.