Aeschbacher S, Mongiat M, Bernasconi R, et al. - Using a population-based sample of adults aged 25-41 years, researchers examined the link between the aldosterone-to-renin ratio (ARR) and many blood pressure (BP) indices among young adults from the general population. All patients were assessed by taking conventional and 24-hour BP recordings. Measurements for direct renin concentration and plasma aldosterone levels were obtained. The study sample comprised 1,353 people (mean age 37 years, 56% women). Across gender-specific ARR quartiles, all BP indices were higher. For conventional, 24-hour, daytime, and nighttime systolic BP, the multivariable-adjusted β-coefficients were estimated to be 1.68; 2.40; 2.23; and 2.80, respectively, per 1-unit increment in log-transformed ARR. For conventional, 24-hour, sustained and masked hypertension, the estimated multivariable-adjusted odds ratio per 1-unit rise in log-transformed ARR were 1.70; 1.29; 1.82; and 1.14, respectively. Findings revealed a strong link of ARR with conventional and ambulatory BP among young adults. The observations are indicative of a very early occurrence of aldosterone-driven phenomenon in hypertension development.