Birukov A, et al. - Given that in healthy pregnancy, the mineralocorticoid aldosterone increases in plasma along with renin and angiotensin II and plays a key role in the physiological plasma volume expansion, researchers examined the relationship of aldosterone with placental and birth weight in humans, and determined if high dietary sodium and low potassium intakes affect this relationship. A subsample of 569 pregnant women from the Odense Child Cohort—a Danish population-based longitudinal cohort study, provided 24-hour urine and plasma samples from gestational week 29 for this analysis. As per outcomes, there is an independent link between urinary aldosterone excretion at gestational week 29 and placental and birth weights. Risk factor for preeclampsia was high salt intake. In perspective, adverse trophic effects were evident with the suppression of aldosterone in pregnancy.