Dohrmann T, Muschol NM, Sehner S, et al. - In this retrospective study, researchers evaluated independent risk factors for perioperative adverse events in people with mucopolysaccharidoses/mucolipidoses and explored the interaction with the primary airway technique implemented. Participants in the study were people with mucopolysaccharidoses/mucolipidoses who had anesthesia at two high‐volume centers from 2002 to 2016. Of 141 reported inpatients, 67 (63 mucopolysaccharidoses and 4 mucolipidoses) had 269 anesthesia procedures (study cases) for 353 surgical or diagnostic interventions. The authors discovered that perioperative adverse events risk was higher in mucopolysaccharidoses type I or type II than in type III. Fiberoptic intubation by a supraglottic airway was linked to the lowest risk for perioperative adverse events and lowest conversion rate. Findings suggested an association of direct laryngoscopy with a significantly higher risk for airway management problems than indirect techniques. The most important independent risk factors for perioperative adverse events were the disease subtype and primary airway technique. The results suggest that in mucopolysaccharidoses/mucolipidoses children with predicted difficult airway indirect techniques should be favored for the first attempt at tracheal intubation.