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Air pollution exposure during pregnancy: Maternal asthma and neonatal respiratory outcomes

Annals of Epidemiology Jun 18, 2018

Seeni I, et al. - Considering the observation that maternal asthma increases adverse neonatal respiratory outcomes and pollution may further increase risk, researchers sought for the relation of air quality to neonatal respiratory health. Using medical records among 223,375 singletons from the Consortium on Safe Labor (2002-2008), they identified transient tachypnea of the newborn (TTN), asphyxia, and respiratory distress syndrome (RDS). As per this analysis, several pollutants seem to increase neonatal respiratory outcome risks. They observed an increase in TTN risk after particulate matter (PM) ≤10 microns exposure during preconception and trimester one (9-10%), and whole pregnancy exposure to PM≤2.5 microns (PM2.5) (17%) and carbon monoxide (CO) (10%). Increase in asphyxia risk was observed after exposure to PM2.5 in trimester one (48%) and whole pregnancy (84%), CO in trimester two and whole pregnancy (28-32%), and consistently for ozone (34-73%). Association of RDS risk with increased concentrations of nitrogen oxides (33-42%) and ozone (9-21%) during all pregnancy windows was observed.
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