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Air pollution exposure and lung function until age 16: The PIAMA birth cohort study

European Respiratory Journal Aug 29, 2018

Milanzi EB, et al. - Researchers examined the associations of air pollution exposure with forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) growth from ages 8 to 16 and FEV1 and FVC at age 16, both longitudinally (N=915) and cross-sectionally (N=721). They observed reduced FEV1 growth, and lower FEV1, in relation to higher air pollution exposure. No adverse association of higher air pollution exposure with FVC was noted. Boys vs girls showed stronger associations with FEV1 and these links were not modified by asthma status. Overall, they concluded that, increased airway obstruction, but not reduced lung volume, may be seen in adolescence as a consequence of higher air pollution exposure.
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