Age‐related suppression effect of current body weight on the association between birthweight and blood pressure: The Bogalusa heart study
Pediatric Obesity Aug 29, 2020
Yun M, Wang X, Fan L, et al. - In the present study, the researchers sought to partition the total effect of birthweight on blood pressure (BP) into its direct effect and indirect effect through the current body mass index (BMI). The sample consisted of 6,251 participants who had birthweight information with 13,443 observations on BMI and BP in pre‐adolescence (4‐11 years), adolescence (12‐19 years), young adulthood (20‐30 years) and mid‐adulthood (31‐58 years). Findings suggested that current body weight has a suppression effect on the birthweight‐BP association, not a mediation effect, with pre‐adolescents having the greatest suppression effect. The suppression effect is mainly determined by associations between birthweight-BMI and BMI‐BP.
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