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Adverse pregnancy outcomes among individuals with and without severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): A systematic review and meta- analysis

Obstetrics and Gynecology Apr 02, 2021

Huntley BJF, Mulder IA, Di Mascio D, et al. - The risk of intrauterine fetal death (20 weeks of gestation or later) and neonatal death was compared between individuals who tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vs those who tested negative for SARS-CoV-2 on admission for delivery. Researchers herein searched MEDLINE, Ovid, EMBASE, Cumulative Index to Nursing and Allied Health, and Cochrane Library from their inception until July 17, 2020, identifying a total of 941 articles and completed trials; inclusion was performed of six studies. When admitted to labor and delivery, individuals who tested positive were similar to those who were negative for SARS-CoV-2 with respect to the incidences of intrauterine fetal death and neonatal death. In addition, newborns born to individuals who tested positive were similar to those born to negative individuals for SARS-CoV-2 with respect to other immediate outcomes of the newborns.

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