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Adverse birth outcomes among mothers who received intermittent preventive treatment with Sulphadoxine-Pyrimethamine in the low malaria transmission region

BMC Pregnancy and Childbirth Jul 15, 2019

Mikomangwa WP, et al. - Researchers sought to determine the burden of preterm delivery, low birth weight (LBW), maternal and fetal anemia in the low malaria transmission region of Tanzania. At Mwananyamala referral hospital in Dar es Salaam, they conducted a study involving 631 pregnant women from April to August 2018. They enrolled the participants prior to delivery, and performed the structured interview and used antenatal clinic cards to obtain data including the use of intermittent preventive therapy in pregnancy using sulfadoxine-pyrimethamine (IPTp-SP). Outcomes revealed a high prevalence of preterm delivery, maternal anemia, LBW and fetal anemia in Tanzania despite the reduced malaria transmission and use of IPTp-SP. They recommend continued use of the recommended ≥3 doses of IPTp-SP, even in areas with substantial reduction of malaria.
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