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Advanced maternal age and risk of adverse perinatal outcome among women with congenital heart disease: A nationwide register‐based cohort study

Paediatric and Perinatal Epidemiology Mar 27, 2020

Kloster S, et al. - Researchers examined if women with and without congenital heart disease differ in the pattern of higher risk of preterm birth (PTB) and small for gestational age (SGA) with higher maternal age. It was hypothesized that women with congenital heart disease may exhibit higher effect of age. Danish nationwide registers yielded data from 932,772 births among 548,314 women from 1997 to 2014. Outcomes suggest a higher risk of PTB and giving birth to an SGA infant at all maternal ages among women with congenital heart disease. However, these two risk factors seemed not potentiating each other.   . 

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