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Adolescent obesity and midlife cancer risk: A population-based cohort study of 2·3 million adolescents in Israel

The Lancet Diabetes & Endocrinology Mar 04, 2020

Furer A, Afek A, Sommer A, et al. - In this nationwide, population-based cohort study involving 2,298,130 candidates (928,110 were women and 1,370,020 were men), researchers analyzed correlations between measured BMI at age 17 years and cancer incidence, and with mortality among those who developed cancer. During 1967–2010, adolescents, height and weight were measured at pre-recruitment mandatory medical examination. Of the 2,458,170 candidates examined between January 1, 1967, and December 31, 2010, 160,040 were eliminated. Data reported that the projected population attributable risk for high BMI was 5·1% for men and 5·7% for women. The increasing prevalence of adolescent obesity and the possible correlation between adolescent BMI and cancer incidence could increase the future burden of cancers associated with obesity. BMI among adolescents could be an important target for cancer prevention interventions.
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