Yu T, Bo Y, Chang LY, et al. - In this investigation involving 463,002 adults, researchers sought to compare the correlations of mortality with body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR), and body fat percentage (BF%) in a prospective cohort. Adults were selected between 1996 and 2017. To test the associations of BMI, WC, WHtR, and BF% with mortality, Cox proportional hazards model was used. For all four parameters, clear U-shape relationships have been observed. The lowest risk of mortality was observed in the BMI category of 23.5–24.9 kg/m² in both men and women. The findings indicate that BMI should continue to be the primary marker for excessive adiposity screening. However, when evaluating the risk of mortality, the results also endorse the use of WC, WHtR, and/or BF%, in addition to BMI.