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Adiponectin is associated with insulin sensitivity in white European men but not black African men

Diabetic Medicine Apr 08, 2021

Hakim O, Bello O, Ladwa M, et al. - In the present study, the researchers sought to evaluate ethnic differences in inflammatory markers and their associations with insulin sensitivity and regional adiposity between white European and black African men. Inflammatory markers were measured alongside Dixon-magnetic resonance imaging to quantify subcutaneous and visceral adipose tissue, as well as intrahepatic lipid, in 53 white European and 53 black African men. The black African men showed significantly lower adiponectin and tumour necrosis factor‐α (TNF‐α) and greater interleukin‐10 than white European men. Although adiponectin levels are lower in black African men, its insulin sensitising effects may be greater in white men, implying that adipokines' involvement in the development of type 2 diabetes may vary by ethnicity.

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