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Acute kidney injury and risk of heart failure and atherosclerotic events

Clinical Journal of the American Society of Nephrology May 27, 2018

Go AS, et al. - In this retrospective analysis, researchers investigated if AKI is independently related to a higher risk of different cardiovascular events in the first year after hospital discharge. A cohort was analyzed between 2006 and 2013 with follow-up through 2014, within Kaiser Permanente Northern California. Using electronic medical records, the occurrence of heart failure, acute coronary syndromes, peripheral artery disease, and ischemic stroke events was traced during the 365 days after discharge. Findings demonstrated an independent association of AKI with a higher risk of cardiovascular events, especially heart failure, after hospital discharge even after adjustment for demographics, comorbidities, preadmission eGFR and proteinuria, heart failure and sepsis complicating the hospitalization, intensive care unit admission, length of stay, and predicted in-hospital mortality.
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