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Acute kidney injury after liver resection in elderly patients

BMC Nephrology Jul 26, 2019

Dedinská I, et al. - Given that acute kidney injury (AKI) influences about 13% of patients undergoing major abdominal surgery, researchers retrospectively examined 785 patients who underwent liver resection, to determine risk factors for AKI in elderly patients with no known kidney disease at the time of operation and to assess their 30-day, 12-month and 5-year survival. Male gender, histological detection of colorectal carcinoma metastases, surgery duration longer than 300 min, blood loss of more than 500 ml, and the requirement for more than 500 ml of fresh frozen plasma during surgery ml were identified as independent risk factors for AKI. Patients older than 65 years (n = 76) vs younger patients (n = 119) had a significantly higher incidence of complications. Younger patients who developed AKI experienced significantly worse 30-day survival. Based on the findings, highly individualized approaches to treatment are recommended, including the evaluation of many variables. Since it was not confirmed in this study that age is an independent risk factor for AKI, age should not present as a contraindication for the indication of a patient for surgery.
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