Cesareo A, et al. - Given that mechanical insufflation-exsufflation (MI-E) is clinically beneficial in patients with chronic airway secretion obstruction and muscular weakness and is suggested as useful in Duchenne muscular dystrophy (DMD) patients when they are stable with no airway infections, researchers aimed to report the effect of MI-E specifically on stable DMD patients who have adapted to the use of MI-E. On analyzing 20 subjects with DMD using MI-E device regularly at home, it was noted that a single treatment of MI-E can provide beneficial changes in breathing pattern through a significant decrease in breathing frequency and rapid shallow breathing. Despite no changes in lung-volume recruitment or unassisted cough peak flow, an improvement in short-term dyspnea was reported.