Maheshwari K, Nathanson BH, Munson SH, et al. - Researchers examined the value of a single abnormal shock index reading (SI ≥ 0.9; heart rate/systolic blood pressure [SBP]) for predicting mortality, and the relationship between cumulative abnormal SI exposure and mortality/morbidity. They assessed 18,197 patients with an ICU stay ≥ 24-h (years 2010–2018) from 82 hospitals in this cohort study. Via cumulative minutes or time-weighted average, evaluation of SI ≥ 0.9 exposure was performed; analysis of SBP ≤ 100-mmHg was done. The analysis revealed the poor predictive value of a single SI reading ≥ 0.9 for mortality; there was an association of cumulative SI exposure with a greater risk of mortality/morbidity. For SI ≥ 0.9 or SBP ≤ 100-mmHg exposure, comparable associations with in-hospital mortality were evident.