Wu N, et al. - A retrospective study was done to identify risk factors for opaque bubble layer (OBL) formation and compare the incidence of OBL utilizing a cone modification technique versus the original technique for LASIK flap creation utilizing the VisuMax laser (Carl Zeiss Meditec, Jena, Germany). Less astigmatic, thicker, denser, and smaller corneas increased the risk of OBL utilizing the original technique for flap creation. The cone modification technique was related to lower risk of OBL formation, even in eyes with significant risk factors for OBL utilizing the original technique.