Hart E, Nguyen M, Allen M, et al. - Researchers examined how antifungal stewardship (AFS) interventions in the United states influenced clinical and performance measures. Searching the PubMed and EMBASE databases, they identified 54 articles; of these 13 were included in this work. With an overall rate of 27% in the intervention group and 23% in the non-intervention group, the analysis revealed no influence of AFS programs on mortality (3 of 3 studies); on length of stay (LOS; 5 of 5) the results of these groups were also comparable, with LOS ranges of 9–25 vs 11–22, respectively. Two of 5 studies showed improved time to antifungal therapy, and 2 of 2 studies showed an increase in the appropriate choice of antifungal. Following stewardship initiation, there was significant dampened or reduced antifungal consumption (8 of 8). The available evidence suggests that performance measures can be improved and antifungal consumption can be reduced via implementing AFS interventions. Despite no detection of improvements in clinical outcomes, there was no report of significant adverse outcomes.