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A state-wide population-based evaluation of cervical cancers arising during opportunistic screening in the United States

Gynecologic Oncology Sep 27, 2020

Landy R, Mathews C, Robertson M, et al. - As per estimates, 13,800 women will be diagnosed with cervical cancer in the United States in 2020 despite widespread cervical screening. Researchers sought to report on the screening histories of women diagnosed with cervical cancer in New Mexico in order to inform improvements. From 2006 to 2016, 504 women were diagnosed with cervical cancer. For 64% of these women, no screening or only inadequate screening tests were reported in the 5–40 months prior to diagnosis, and only negative screens were recorded in this period for 90 of 182 screened women (49%). Per observations, currently, 35% of cancers are averted by screening; full screening coverage could avert 61% of cancers. Among cervical cancers, one-third were screen-detected (ie, diagnosed within 4 months of a positive screen). A negative screen was reported for 72% of the adenocarcinomas in a 3-yr period prior to diagnosis. Nine percent of cancers were linked with a failure to receive recommended diagnostic biopsy or treatment (failsafe failure). Findings here suggest that for reducing cervical cancer incidence, improved screening coverage has the largest potential, though improved recall procedures and screening sensitivity also play a role.

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