Kosinski C, Herzig D, Laesser CL, et al. - Researchers here examined if the risk of exercise-induced hypoglycemia reduces with preexercise intake of fructose among individuals with type 1 diabetes using insulin degludec in correlation. They conducted a randomized two-period crossover study including 14 male adults with type 1 diabetes; the participants completed two 60-min aerobic cycling sessions with or without prior intake (30 min) of 20 g of fructose. They observed one hypoglycemic event at 60 min with intake of fructose vs six hypoglycemic events at 27.5 ± 9.4 min of exercise in the control condition, translating into a risk reduction of 87.8%. Findings suggest preexercise intake of fructose as an easily feasible, effective, and well-tolerated strategy to reduce the risk of exercise-induced hypoglycemia while avoiding hyperglycemia in cases with type 1 diabetes on ultra-long-acting insulin.