Du D - In this crossover study, researchers assessed new mint-flavored nicotine gum (2 and 4 mg strengths) for bioequivalence vs the original flavor sugar-free nicotine gum at corresponding dosages. Participants in the study received a single dose of all treatments, ie, 2 and 4 mg doses of test and reference gums, separated by 2–7 days of washout between treatments. Data reported that the new mint-flavored nicotine gum with modified taste and texture was bioequivalent to the original flavor sugar-free nicotine gum at both the 2 and 4 mg dosage strengths. The safety profiles of the test and reference gums were similar.