Ellis RJ, Del Vecchio SJ, Gallagher KMJ, et al. - Researchers intended to create a tool for stratifying patients’ risk of CKD originating following surgery for kidney cancer. For this purpose, they tested models in a population-based cohort comprising 699 patients suffering from kidney cancer in Queensland, Australia (2012–2013). For validation, they opted a population-based cohort including 423 patients from Victoria, Australia, and patient cohorts from single centers in Queensland, Scotland, and England. Incident eGFR < 45 ml/min per 1.73 m² at 12 months after nephrectomy was considered as the main outcome. Prespecified predictors such as age ≥ 65 years old, diabetes mellitus, preoperative eGFR, and nephrectomy type (partial/radical) were used to fit logistic regression models. Patients were categorized based on degree of risk of clinically significant CKD (negligible, low, moderate, or high risk). Across the 4 strata of negligible, low, moderate, and high risk, the absolute risks of stage 3b or higher CKD were estimated to be < 2%, 3% to 14%, 21% to 26%, and 46% to 69%, respectively. Overall, CKD risk after nephrectomy could be reproducibly stratified with this simple scoring system, based on easily available parameters. The quantitative evaluation of CKD risk by this clinical tool may be weighed against other considerations when planning treatment of renal tumors and aid inform shared decision making between clinicians and patients.