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A retrospective cohort study of the management and outcomes of children hospitalized with Stevens-Johnson syndrome or toxic epidermal necrolysis

The Journal of Allergy and Clinical Immunology: In Practice Jun 06, 2018

Antoon JW, et al. - The researchers aimed at characterizing the current management and outcomes of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) across U.S. children’s hospitals. A retrospective cohort study of 898 pediatric patients less than 18 years of age hospitalized with a primary diagnosis of SJS or TEN was performed at 47 U.S. freestanding children’s hospitals. Observations revealed that in children with SJS and TEN, survival was significantly better than observed in adults. However, management and outcomes in children diagnosed with these severe cutaneous reactions varied.
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