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A retrospective cohort study examining STI testing and perinatal records demonstrates reproductive health burden of chlamydia and gonorrhea

Pathogens and Disease Sep 13, 2020

Callan T, Debattista J, Berry B, et al. - As Chlamydia trachomatis and Neisseria gonorrhoea infections have been correlated with adverse reproductive health outcomes, such as pelvic inflammatory disease, ectopic pregnancy, and tubal factor infertility, researchers sought to conduct a cohort study of women in Queensland (QLD), Australia, utilizing data linkage methods to correlate chlamydia and/or gonorrhea testing records (including an unexposed group undergoing full blood count tests) (2000 and 2005) with the QLD Perinatal Registry (2000 to 2013). Among 132,962 women included in the cohort, there were 69,533 records of pregnancies. A reduced odds of a pregnancy was observed during the follow up of the study among women in the exposed group, with no prior pregnancy. Increased odds of pregnancy during the follow up of the study were observed among women in the exposed group with a prior pregnancy. The data yield further evidence at a population level of the significant impact of chlamydia and gonorrhea on reproductive outcomes.

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